Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp300 | Osteoporosis: treatment | ECTS2014

Resveratrol supplementation increases vBMD at the spine in obese men: a randomized controlled trial

Ornstrup Marie Juul , Harslof Torben , Kjaer Thomas Nordstrom , Paulsen Soren Kildeberg , Langdahl Bente Lomholt , Pedersen Steen Bonlokke

Background: Resveratrol (RSV) is a natural polyphenolic compound, found in fx grapes, which possesses anti-inflammatory properties. RSV inhibits osteoclast activity and promotes osteoblastogenesis in vitro. Furthermore, RSV protects against bone loss after ovarectomy and immobilization in animal models. RSV treatment of obese men for 4 weeks resulted in an increase in bone specific alkaline phosphatase (BAP).Hypothesis: Low-grade inflammation is...